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DIABETES DIGEST – Nov. 17, 2014 – If you want to lose weight, you might try exercising in the cold. More research is out this week showing that the key to weight-loss is burning what is called brown fat, or more technically, brown adipocytes.
When you are cold the nervous system activates receptors on the surface of brown fat cells to stimulate glucose uptake from the bloodstream. Brown fat tissue is able to take up large amounts of glucose from the bloodstream to use as fuel to generate body heat.
In a research study in mice, published in The Journal of Cell Biology, Swedish researchers have identified that the signaling pathway, or a cell circuit that regulates this uptake of blood sugar in brown fat is different from the cell circuit that regulates blood sugar uptake triggered by insulin.
"This means that the signal pathway in brown fat can most likely be activated even in patients with type 2 diabetes, where insulin signaling is impaired,” senior author Tore Bengtsson from the Department of Molecular Biosciences, Wenner-Gren Institute, Stockholm University said.
The finding suggests that stimulating this energy-burning brown fat might be an effective weight-loss therapy. In other words, exercising in the cold could increase your weight-loss.
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