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| Blausen.com staff via Wikipedia |
DIABETES DIGEST – Feb. 12, 2015 – If you have type 2 diabetes, lowering your blood pressure may lower your risk of heart disease and dying from cardiovascular disease, according to an analysis of 40 clinical trials dating back to 1966.
The study looked at data from more than 100,000 people who participated in large randomized clinical trials that included an analysis of blood pressure-lowering treatments and vascular disease in type 2 diabetes. The new analysis appeared in the Feb. 10 Journal of the American Medical Association.
Led by Connor A. Emdin, HBSc and Kazem Rahimi, DM, MSc, both of the George Institute for Global Health, University of Oxford, Oxford, U.K, the researchers found that each 10-mm Hg lower systolic BP was associated with a lower risk of mortality, cardiovascular disease events, coronary heart disease events, stroke, albuminuria (the presence of excessive protein in the urine), and retinopathy (loss of vision related to diabetes).
In an accompanying editorial Bryan Williams, M.D., of University College London noted that current guideline recommend lowering blood pressure in patients with type 2 diabetes with antihypertensive treatment when their systolic BP is 140 mm Hg or greater, and aim for a target systolic BP of 130 mm Hg but not usually lower.
“However, the findings of the study by Emdin et al suggest that for some patients, these treatment thresholds and targets might be too conservative, especially for optimally reducing the risk of stroke and the development or progression of albuminuria.”
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